Program Agenda

Monday, November 11, 2019

(07:00-07:45 Breakfast)

07:45     Welcome and Introduction – Dawn Coleman and Rulan Parekh

08:00     Opening Comments – Charles Burant, MD – Taubman Institute Director

08:15 – 10:45:  Scientific Session 1
Pediatric Renovascular Hypertension: Background and Scientific Research Efforts

(Moderator:  S Ganesh + J Stanley)

1. Mendelian Forms of Renovascular Disease – Kevin Meyers, Children’s Hospital of Philadelphia, University of Pennsylvania
2. A Histopathologic Review of Renal Artery Stenosis  – James Stanley, CS Mott Children’s Hospital, University of Michigan
3. The Science Behind NF1 Arteriopathy – David Gutmann, Washington University School of Medicine
4. Gene Discovery – Santhi Ganesh, University of Michigan
5. Epidemiology, Phenotyping and Cohort Development – Rulan Parekh, The Hospital for Sick Children, University of Toronto
6. Whole Exome Sequencing in Midaortic Syndrome – Jillian Warejko, Yale New Haven Children’s Hospital, Yale University School of Medicine
7. Genetic Causes of Renovasuclar Hypertension – Daan Viering, Radboud University Medical Centre

 (10:45 – 11:00 Coffee Break)

11:00-12:00:  Keynote– Harry C. Dietz III, Director of the William S. Smilow Center for Marfan Syndrome, Johns Hopkins University Medical School

(12:00-13:00 Lunch)

13:00 – 15:00:  Scientific Session 2
Pediatric Renovascular Hypertension: General Considerations

(Moderators:  K Tullus + Z Modi)

1. Clinical Manifestations and Natural History of Pediatric Renovascular Hypertension – Kjell Tullus, Great Ormond Street Hospital for Children
2. A Systematic Review of Midaortic Syndrome in Children – Rulan Parekh, The Hospital for Sick Children, University of Toronto
3. Syndrome Diseases and Indications for Patient and Family Genetic Screening – Do Results Impact Management – Santhi Ganesh, University of Michigan
4. Should Pediatric Renal Artery Stenosis/Midaortic Syndrome be Qualified as ‘Pediatric FMD’?  Differences Between the Pediatric and Adult Presentation of FMD:  Results from the US Registry – Kevin Meyers, Children’s Hospital of Philadelphia, University of Pennsylvania
5. Multi-disciplinary Care of the Complex Renovascular Hypertension Patient – Michael Ferguson, Boston Children’s Hospital, Harvard Medical School

(15:00-15:20 Coffee Break)

15:30 – 16:30:  Panel – Building a Multi-Disciplinary Program (M Ferguson, J Flynn, K Meyers, K Tullus, W Sandmann)

(Moderator:  D Coleman + R Parekh)

17:00 – 20:00:  Working Groups A/B (By Invitation)

Tuesday, November 12, 2019

07:30-8:00 – Breakfast

08:00-09:45:  Scientific Session 3
Imaging of Pediatric Renovascular Hypertension

(Moderators:  J Amaral + M Khaja)

1. The Role of Duplex Ultrasound for Diagnosis and Surveillance – Jonathan Dillman, Cincinnati Children’s Hospital Medical Center, University of Cincinnati
2. Cross-Sectional Imaging Considerations:  Balancing the Risks of Cross-Sectional Imaging (CTA v. MRA) – Hansel Otero, Children’s Hospital of Philadelphia, University of Pennsylvania
3. Role of Diagnostic Angiography and Cutting Balloon Angioplasty for Renovascular Hypertension – Anne Marie Cahill, Children’s Hospital of Philadelphia, University of Pennsylvania
4. Fetal and neonatal imaging of aortic and renovascular hypertension – Rajesh Krishnamurthy, Nationwide Children’s Hospital, The Ohio State University
5. Intravenous Digital Subtraction Angiography in the assessment of the Occlusive Disease of the Aorta and Its Branches in Children– Kyung Cho, CS Mott Children’s Hospital, University of Michigan
6. Computational Imaging of Fluid-Structure Interactions and Hemodynamics in Assessing Abdominal Aortic Coarctation and Renal Stenotic Disease – Alberto Figueroa, University of Michigan

(09:45 – 10:00 Coffee Break)

10:00 – 1200:  Scientific Session 4
Medical Management and Surveillance of Pediatric Renovascular Hypertension

(Moderators:  M Ferguson + C Hanevold)

1. What Qualifies as a Medical Treatment Failure:  Indications for Revascularization – David Kershaw, CS Mott Children’s Hospital, University of Michigan
2. Current Guidelines for Medical Therapy and Surveillance – Joseph Flynn, Seattle Children’s Hospital, University of Washington
3. Management of Concurrent Neurovascular Disease – Mahendra Moharir, The Hospital for Sick Children, University of Toronto
4. Management of Neurovascular Complications – Michael Rivkin, Boston Children’s Hospital, Harvard Medical School
5. Management of Concurrent Cardiopulmonary Disease and Complications – Luc Mertens, The Hospital for Sick Children, University of Toronto
6. Long-term Developmental and Cognitive Risks of Hypertension – Marc Lande, University of Rochester Medical Center

(12:00-13:00 Lunch)

13:00 – 16:30:  Scientific Session 5
Interventional Treatment Considerations in neonates/infants – Premal Patel, Great Ormond Street Hospital for Children

(Moderators:  K Meyers + J Eliason)

1. Endovascular Interventions in Pediatric Renovascular Hypertension:  Indications and Limitations – Joao Amaral, The Hospital for Sick Children, University of Toronto
2. Emerging Endovascular Strategies for Diagnosis and Treatment – Diego Porras, Boston Children’s Hospital, Harvard Medical School
3. Interventional Radiology Treatment Considerations in the Small Child – Premal Patel, Great Ormond Street Hospital for Children
4. Open Surgical Revascularization of Pediatric Renovascular Hypertension – Dawn Coleman, CS Mott Children’s Hospital, University of Michigan

(14:30-14:45 Coffee)

• Novel Surgical Treatments – Heung Bae Kim, Boston Children’s Hospital, Harvard Medical School
• Renal Auto-Transplantation – Armando Lorenzo, The Hospital for Sick Children, University of Toronto
• Remedial / Salvage Surgical Procedures for Treatment Failures – Jonathan Eliason, CS Mott Children’s Hospital, University of Michigan
• Treatment of Segmental Disease in Pediatric Renal Artery Disease:  The role for partial nephrectomy – John Park, CS Mott Children’s Hospital, University of Michigan

16:30-16:45:  Closing Remarks – D Coleman and R Parekh

17:00 – 20:00:  Working Groups C/D (By Invitation)